鈍葉大果漆

出自台灣有毒中草藥毒性資料庫

基本資料

科別	漆樹科Anacardiaceae
屬名	大果漆樹屬 Semecarpus
中文學名	鈍葉大果漆
拉丁學名	Semecarpus cuneifomis Blanco.
英文名稱
中文俗名	小葉大果漆，鈍葉番漆

[1, 2]

植物圖片

尚未有授權圖片

鈍葉大果漆簡介

常綠小喬木，株高可達5公尺[1]

外觀簡述

葉	葉互生，長橢圓形，先端鈍或圓，長7-18公分，革質全緣[1]寬3.4-6公分，無毛或極微被短柔毛
花	為圓錐花序頂生，兩性花，花冠為披針形，長可達15公分，花瓣白色或淡黃色
果實	核果近卵形，果托膨大，熟果為橙紅色

產地

分布於菲律賓、西里伯島，台灣原產於蘭嶼山區林緣或向陽的山坡地[1, 2]

使用情況

樹汁用於無痛潰瘍、非出血性痔瘡，也可用於腹水、支氣管痙攣及腫瘤[3]的輔助療法，另外膠樹脂已被用於痲瘋病和神經衰弱

活性成份[4,5]

樹皮與果實	1. biflavoinoids 2. phenolic compounds 3. bhilawanols, minerals
葉	1. amentoflavone
果殼	1. biflavonoids 2. biflavones 3. tetrahydrorobustaflavone 4. jeediflavone 5. semecarpuflavone 6. gulluflavone.
果油	1. bhilavinol

活性研究

抗氧化、抗風濕發炎、抗腫瘤，降血糖、抗黴菌，神經保護[6]

毒性研究

症狀[7,8]
- 1. 腎髓質細胞壞死引起的腎衰竭
- 2. 貧血

有毒成分[8]
- 1. oil extract

中毒劑量
- 未知

機轉[8]
- 1. The depletion of RBC number as well as Haemoglobin content may probably be due to defective haematopoiesis

案例報導[7]
- An 18-year-old man developed skin lesions and anuria following exposure to sap of the marking-nut tree. Renal biopsy showed diffuse cortical necrosis. The mechanism of nephrotoxicity of the sap is unknown but may be due to its phenolic constituents.

血液毒性[8]
- (83.33 mg to 750 mg/kg b w/day) nut oil extract induced severe anaemia

毒性分級

級數B

參考文獻

1. 薛聰賢. 台灣原生景觀植物圖鑑. 台灣普綠有限公司 2004.

2. LI H-L. Flora of Taiwan, second edition (台灣植物誌第二版). 1993.

3. Mathivadhani P, Shanthi P, Sachdanandam P. Apoptotic effect of Semecarpus anacardium nut extract on T47D breast cancer cell line. Cell Biol Int 2007; 31: 1198-1206.

4. Lingaraju GM, Hoskeri HJ, Krishna V, Babu PS. Analgesic activity and acute toxicity study of Semecarpus anacardium stem bark extracts using mice. Pharmacognosy Res 2011; 3: 57-61.

5. Vijayalakshmi T, Muthulakshmi V, Sachdanandam P. Toxic studies on biochemical parameters carried out in rats with Serankottai nei, a siddha drug-milk extract of Semecarpus anacardium nut. J Ethnopharmacol 2000; 69: 9-15.

6. Semalty M, Semalty A, Badola A et al. Semecarpus anacardium Linn.: A review. Pharmacogn Rev 2010; 4: 88-94.

7. Matthai TP, Date A. Renal cortical necrosis following exposure to sap of the marking-nut tree (Semecarpus anacardium). Am J Trop Med Hyg 1979; 28: 773-774.

8. CHOUDHARI CV, DESHMUKH PB. ACUTE AND SUBCHRONIC TOXICITY STUDY OF SEMECARPUS ANACARDIUM ON HAEMOBLOBIN PERCENT A ND RBC COUNT OF MALE ALBINO RAT. Journal of Herbal Medicine and Toxicology 2007; 1: 2.