http://tcm-toxic.kmu.edu.tw/index.php?action=history&feed=atom&title=Baclofen_%E4%B8%AD%E6%AF%92 2026-07-25T18:18:43Z 本站上此頁的修訂歷史 MediaWiki 1.16.2 http://tcm-toxic.kmu.edu.tw/index.php?title=Baclofen_%E4%B8%AD%E6%AF%92&diff=2333&oldid=prev 2012-07-05T03:01:47Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←上一修訂</td> <td colspan='2' style="background-color: white; color:black;">在2012年7月5日 (四) 03:01所做的修訂版本</td> </tr><tr><td colspan="2" class="diff-lineno">第1行：</td> <td colspan="2" class="diff-lineno">第1行：</td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">&lt;font size=5 color=green&gt;</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">1. Baclofen 中毒機轉&lt;/font&gt; &lt;font size=4&gt;</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*1) 抑制 substance P，抑制 dopamine 釋放</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*2) 具有 GABA 協同作用</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*3) 鉀離子傳導率的增加，增加抑制性的神經傳導物質的釋出</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*4) 鈣離子傳導率的降低而減少興奮性神經物質的釋出，解除橫紋肌的痙攣&lt;/font&gt;</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">&lt;font size=5 color=green&gt;</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">2. Baclofen 中毒的症狀&lt;/font&gt;</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">&lt;font size=4&gt;</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*1)早期：躁動</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*2) 3-5 小時： 四肢無力、昏迷、呼吸抑制、抽搐、譫妄、低血壓、心搏變緩、低體溫</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*3) 12-96 小時：戒斷症狀，抽搐、幻覺、失眠、神智混亂、躁動</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*4) 未治療：可能持續至 8 天之久&lt;/font&gt;</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">&lt;font size=5 color=green&gt;</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">3. Baclofen 中毒的治療&lt;/font&gt;</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">&lt;font size=4&gt;</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*1) 活性碳、洗胃、以支持療法為主，但不催吐</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*2) 應注意心跳、血壓、呼吸的照顧</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*3) 強迫利尿或血液透析</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*4) 抽搐：diazepam, lorazepam, phenobarbital and/or phenytoin</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*5) 低血壓： 補充水份、升壓劑</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">*6) 產生戒斷症狀者：治療劑量的 baclofen&lt;/font&gt;</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[http://tcm-toxic.kmu.edu.tw/index.php/%E5%B8%B8%E8%A6%8B%E4%B8%AD%E6%AF%92%E8%99%95%E7%90%86%E6%96%B9%E5%BC%8F 返回常見中毒處理方式]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[http://tcm-toxic.kmu.edu.tw/index.php/%E5%B8%B8%E8%A6%8B%E4%B8%AD%E6%AF%92%E8%99%95%E7%90%86%E6%96%B9%E5%BC%8F 返回常見中毒處理方式]</div></td></tr> </table>

Kmutox520 http://tcm-toxic.kmu.edu.tw/index.php?title=Baclofen_%E4%B8%AD%E6%AF%92&diff=2326&oldid=prev 2012-07-05T02:30:05Z

<p>以內容「 [http://tcm-toxic.kmu.edu.tw/index.php/%E5%B8%B8%E8%A6%8B%E4%B8%AD%E6%AF%92%E8%99%95%E7%90%86%E6%96%B9%E5%BC%8F 返回常見中毒處理方式]」創建新頁面</p> <p><b>新頁面</b></p><div><br /> <br /> <br /> [http://tcm-toxic.kmu.edu.tw/index.php/%E5%B8%B8%E8%A6%8B%E4%B8%AD%E6%AF%92%E8%99%95%E7%90%86%E6%96%B9%E5%BC%8F 返回常見中毒處理方式]</div>

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